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AXIN2 抗体 (C-Term)

Name: AXIN2 抗体 (C-Term)
SKU: ABIN651608
Availability: OutOfStock

This anti-AXIN2 antibody is a 兔多克隆 antibody detecting AXIN2 in WB, FACS 和 IHC (p). Suitable for 人.

AXIN2 Antibody (C-term) (ABIN651608 and ABIN2840323) western blot analysis in Jurkat cell line lysates (35 μg/lane). (AXIN2 抗体 (C-Term))

AXIN2 Antibody (C-term) (ABIN651608 and ABIN2840323) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram). (AXIN2 抗体 (C-Term))

FACS

AXIN2 Antibody (C-term) (ABIN651608 and ABIN2840323) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (AXIN2 抗体 (C-Term))

IHC (p)

3 images

产品编号 ABIN651608

发货至: 中国

Quick Overview for AXIN2 抗体 (C-Term) (ABIN651608)

抗原

See all AXIN2 抗体

AXIN2 (Axin 2 (AXIN2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This AXIN2 antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB26798

Discover our top product AXIN2 Primary Antibody

抗原表位
15

8

5

5

5

4

3

2

1

1

1

1
AA 816-843, C-Term

预测反应

M, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This AXIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 816-843 amino acids from the C-terminal region of human AXIN2.

亚型

Ig Fraction
anti-Axin 2 (AXIN2) (AA 650-750) antibody
AXIN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Axin 2 (AXIN2) (AA 816-843) antibody
AXIN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Axin 2 (AXIN2) (AA 56-73) antibody
AXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Axin 2 (AXIN2) antibody
AXIN2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Axin 2 (AXIN2) (AA 331-430) antibody
AXIN2 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Axin 2 (AXIN2) (AA 350-631) antibody
AXIN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Axin 2 (AXIN2) (AA 11-77) antibody
AXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Axin 2 (AXIN2) (AA 611-710) antibody
AXIN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated

anti-Axin 2 (AXIN2) (N-Term) antibody
AXIN2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Axin 2 (AXIN2) antibody
AXIN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

AXIN2 (Axin 2 (AXIN2))

别名

AXIN2

背景

The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.

分子量

93558

基因ID

8313

NCBI登录号

NP_004646

UniProt

Q9Y2T1

途径

Regulation of G-Protein Coupled Receptor Protein Signaling