ATF6B 抗体 (C-Term)
Quick Overview for ATF6B 抗体 (C-Term) (ABIN651294)
抗原
See all ATF6B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 560-589, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CREBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-589 amino acids from the C-terminal region of human CREBL1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells." in: OncoTargets and therapy, Vol. 9, pp. 2519-33, (2016) (PubMed).
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: "Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells." in: OncoTargets and therapy, Vol. 9, pp. 2519-33, (2016) (PubMed).
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- ATF6B (Activating Transcription Factor 6 beta (ATF6B))
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别名
- CREBL1
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背景
- CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.
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分子量
- 76709
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基因ID
- 1388
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NCBI登录号
- NP_001129625, NP_004372
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UniProt
- Q99941
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途径
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
抗原
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