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S100B 抗体

This anti-S100B antibody is a 兔 多克隆 antibody detecting S100B in WB, FACS 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN651265
发货至: 中国

Quick Overview for S100B 抗体 (ABIN651265)

抗原

See all S100B 抗体
S100B (S100 Calcium Binding Protein B (S100B))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This S100B antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB22934
  • 预测反应

    Rb

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This S100B antibody is generated from rabbits immunized with S100B recombinant protein.

    亚型

    IgG
  • 应用备注

    WB: 1:2000. WB: 1:1000. WB: 1:2000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500. FC: 1:10~50. IHC: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    S100B (S100 Calcium Binding Protein B (S100B))

    别名

    S100B

    背景

    S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

    分子量

    10713

    基因ID

    6285

    NCBI登录号

    NP_006263

    UniProt

    P04271

    途径

    Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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