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NFkB 抗体 (pSer536)

The 兔多克隆 anti-NFkB antibody (Clone RB22552) (ABIN650886) specifically detects NFkB in DB. The antibody is reactive with 人 samples.

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产品编号 ABIN650886

发货至: 中国

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Quick Overview for NFkB 抗体 (pSer536) (ABIN650886)

抗原

See all NFkB 抗体

NFkB (Nuclear Factor kappa B (NFkB))

适用

人

宿主

兔

克隆类型

多克隆

标记

This NFkB antibody is un-conjugated

应用范围

Dot Blot (DB)

克隆位点

RB22552

Discover our top product NFkB Primary Antibody

抗原表位
5

2

2

1

1

1

1

1

1

1

1

1
pSer536

预测反应

M

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This NF kappa B Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S536 of human NF kappa B.

亚型

Ig Fraction
anti-Nuclear Factor kappa B (NFkB) (AA 42-367) antibody
NFkB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor kappa B (NFkB) (AA 805-892) antibody
NFkB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor kappa B (NFkB) (AA 352-439) antibody
NFkB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor kappa B (NFkB) (AA 40-365) antibody
NFkB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor kappa B (NFkB) antibody
KD Validated NFkB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Monoclonal unconjugated Recombinant Antibody

anti-Nuclear Factor kappa B (NFkB) antibody
NFkB 适用: 人 CP unconjugated

anti-Nuclear Factor kappa B (NFkB) (AA 47-372) antibody
NFkB 适用: 小鸡 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor kappa B (NFkB) (Subunit 2) antibody
KD Validated NFkB 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2990 unconjugated Recombinant Antibody

anti-Nuclear Factor kappa B (NFkB) (pSer536) antibody
NFkB 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB5212 unconjugated

anti-Nuclear Factor kappa B (NFkB) (pSer536) antibody
NFkB 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

DB: 1:500

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

NFkB (Nuclear Factor kappa B (NFkB))

别名

NF kappa B

背景

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).

分子量

60219

基因ID

5970

NCBI登录号

NP_001138610, NP_001230913, NP_068810

UniProt

Q04206

途径

Ubiquitin Proteasome Pathway, S100 Proteins