LDLRAP1 抗体
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北京 101111
Quick Overview for LDLRAP1 抗体 (ABIN645905)
抗原
See all LDLRAP1 抗体适用
宿主
标记
应用范围
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特异性
- The goat Anti-ARH / LDL receptor antibody detects protein derived from human recombinant protein and human liver lysate at various concentrations.
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交叉反应
- 人, 小鼠
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产品特性
- Goat Anti-ARH / LDL Receptor adaptor
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免疫原
- Peptide with sequence C-DALKSAGRALIRS, from the N Terminus of the protein sequence according to NP_056442.1, was used as immunogen.
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亚型
- IgG
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anti-Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (AA 1-263) antibody
LDLRAP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4G4-D5 unconjugated
anti-Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (AA 1-308) antibodyLDLRAP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (AA 1-264) antibodyLDLRAP1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4G4-D5 unconjugated
anti-Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (N-Term) antibodyVerified LDLRAP1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) antibodyLDLRAP1 适用: 人, 犬 WB 宿主: 小鼠 Monoclonal 7A5 unconjugated
anti-Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (AA 59-308) antibodyLDLRAP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (AA 59-308) antibodyLDLRAP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (AA 11-42), (N-Term) antibodyLDLRAP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12630 unconjugated
anti-Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (AA 277-306), (C-Term) antibodyLDLRAP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB13027 unconjugated
anti-Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) (AA 35-84) antibodyLDLRAP1 适用: 人, 犬, Cow, 兔, 马, Pig, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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溶解方式
- Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.
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储存条件
- -20 °C
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- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
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背景
- LDLRAP1 is an adaptor protein that interacts with the cytoplasmic tail of low density lipoprotein receptor , phospholipids, and components of the clathrin endocytic machinery. LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDLR, LRP, Megalin, VLDLR and apoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. The LDL receptor is a cell surface transmembrane protein that mediates the uptake of low density lipoprotein and its degradation in the lysosome, which provides cholesterol to cells. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. Mutations in LDLR cause the autosomal dominant disease familial hypercholesterolemia (FH), which promotes premature coronary atherosclerosis.
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NCBI登录号
- NP_056442
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途径
- Lipid Metabolism
抗原
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