Retinoid X Receptor beta 抗体
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北京 101111
Quick Overview for Retinoid X Receptor beta 抗体 (ABIN645872)
抗原
See all Retinoid X Receptor beta (RXRB) 抗体适用
宿主
标记
应用范围
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特异性
- The Goat anti-RXR beta antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Goat Anti-RXR beta
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免疫原
- Peptide with sequence CRDGMGDSGRDSRSP, from the internal region of the protein sequence according to NP_068811, was used as an immunogen.
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亚型
- IgG
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限制
- 仅限研究用
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溶解方式
- Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.
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储存条件
- -20 °C
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- Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))
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别名
- RXR beta
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背景
- Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins that exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).
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NCBI登录号
- NP_068811
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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