CBX3 抗体
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北京 101111
Quick Overview for CBX3 抗体 (ABIN645855)
抗原
See all CBX3 抗体适用
宿主
标记
应用范围
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特异性
- The Goat anti-HP1 Gamma / CBX3 antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.
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交叉反应
- 小鼠, 大鼠, 犬
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产品特性
- Goat Anti-CBX3 / HP1 gamma
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免疫原
- Peptide with sequence C-EAFLNSQKAGKEKD, from the internal region of the protein sequence according to NP_009207.2, NP_057671.2, was used as immunogen.
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亚型
- IgG
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限制
- 仅限研究用
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溶解方式
- Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.
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储存条件
- -20 °C
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- CBX3 (Chromobox Homolog 3 (CBX3))
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别名
- CBX3 / HP1 gamma
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背景
- CBX3 antibody is involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
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NCBI登录号
- NP_009207
抗原
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