EBV LMP2A 抗体
This anti-EBV LMP2A antibody is a 大鼠 antibody detecting EBV LMP2A in IHC (p) 和 WB. Suitable for Epstein-Barr Virus (EBV).
Quick Overview for EBV LMP2A 抗体 (ABIN644979)
抗原
EBV LMP2A
(Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
适用
Epstein-Barr Virus (EBV)
宿主
大鼠
标记
This EBV LMP2A antibody is un-conjugated
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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特异性
- DS-MB-03627 recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. DS-MB-03627 specifically recognizes LMP2A and does not cross react with LMP2B.
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产品特性
- Rat Anti-Epstein-Barr Virus LMP2A
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纯化方法
- Purified
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免疫原
- Bacterial TrpE-LMP2A fusion protein
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亚型
- IgG2a
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限制
- 仅限研究用
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浓度
- IgG concentration 1.0 mg/ml
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缓冲液
- Phosphate buffered saline
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
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别名
- Epstein-Barr Virus LMP2A
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物质类
- Viral Protein
抗原
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