Influenza A Virus H1N1 抗体
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北京 101111
Quick Overview for Influenza A Virus H1N1 抗体 (ABIN643615)
抗原
适用
宿主
标记
应用范围
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特异性
- DS-PB-01152 is specific for Influenza A virus H1N1 glycoprotein and does not react with Influenza B, RSV, Para 1-3 or Adenovirus. It does not react with HEp-2 cells but may react with some chicken cellular proteins.
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产品特性
- Goat Anti-Influenza A H1N1
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纯化方法
- Purified
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免疫原
- Influenza A, strain USSR (H1N1)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- IgG concentration 1.0 mg/ml
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缓冲液
- Phosphate buffered saline pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- Influenza A Virus H1N1
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别名
- Influenza A H1N1
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物质类
- Influenza Virus
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背景
- Influenza type A viruses are divided into subtypes based on the antigenic differences of two viral surface proteins, hemagglutinin (H) and neuraminidase (N). On infection of the respiratory tract, the hemagglutinin molecule binds to sialic acid-containing receptors on the epithelial cells resulting in endocytosis. Once the virus has been engulfed, the hemagglutinin allows the viral membrane to fuse with the endosomal membrane. Neuraminidase functions to aid viral release from host cells by cleaving terminal sialic acid residues from carbohydrate moieties on the cell surface. Subtype antigenic variations result from a process known as antigenic drift whereby these surface proteins constantly mutate in order to evade the host immune response. Subtype A (H1N1) was the cause of Spanish flu that killed approximately 500,000 people between 1918-1919.
抗原
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