DS-MB-00619 recognizes the human CD32 antigen, a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). The antigen mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. DS-MB-00619 blocks the binding of IgG to Fc gamma R11 (4). Reacts with: Rhesus Monkey, Dog. Antibody reactivity and working conditions may vary between species.