HCV E2 抗体 (AA 384-665)
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北京 101111
Quick Overview for HCV E2 抗体 (AA 384-665) (ABIN640224)
抗原
See all HCV E2 抗体适用
宿主
标记
应用范围
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抗原表位
- AA 384-665
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特异性
- E2 envelope protein
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产品特性
- Goat Anti-Hepatitic C Virus (HCV) E2 (aa 384-665)
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纯化方法
- Purified
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免疫原
- Recombinant E2 (genotype 1a)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 4-5 mg/ml (OD280nm, E^0.1% = 1.4)
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缓冲液
- 0.01M PBS, pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- HCV E2 (Hepatitis C Virus Envelope Protein E2 (HCV E2))
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物质类
- Viral Protein
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背景
- Uev1A, also designated Uev1, UBE2V1 (for ubiquitin-conjugating enzyme E2 variant 1) and CROC1, shows sequence similarity to other ubiquitin-conjugating enzymes, but lacks the conserved cysteine residue critical for their catalytic activity. Therefore, Uev1A does not have ubiquitin-conjugating activity in vitro. However, constitutive expression of exogenous Uev1A in colon carcinoma cells inhibits their capacity to differentiate upon confluence. Studies on recombinant Uev1A show that it localizes to the nucleus, excluding the nucleolar regions. Uev1A functions with TRAF6, a RING domain protein, to catalyze the synthesis of unique polyubiquitin chains linked through Lysine 63 of ubiquitin. The gene encoding Uev1A maps to human chromosome 20q13.2.
抗原
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