HPV16 E7 抗体
The 小鼠 单克隆 anti-HPV16 E7 antibody is suitable to detect HPV16 E7 in samples from Human Papillomavirus 16 (HPV-16). It has been validated for WB 和 ELISA.
产品编号 ABIN639902
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for HPV16 E7 抗体 (ABIN639902)
抗原
See all HPV16 E7 (HPV-16 E7) 抗体
HPV16 E7 (HPV-16 E7)
(Human Papilloma Virus 16 E7 (HPV-16 E7))
适用
Human Papillomavirus 16 (HPV-16)
宿主
小鼠
克隆类型
单克隆
标记
This HPV16 E7 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
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原理
- Mouse Anti-HPV 16 Oncoprotein E7
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特异性
- DS-MB-03401 recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-suppressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. DS-MB-03401 cross-reacts with both the monomer and dimer forms of the E7 protein of HPV-18.
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产品特性
- Bacterial/Fungal/Parasitic/Viral Antigens
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纯化方法
- Purified
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免疫原
- Oncoprotein E7 from human papillomavirus 16.
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亚型
- IgG2a
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应用备注
- ELISA, Western Blotting
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限制
- 仅限研究用
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浓度
- IgG concentration 1.0 mg/ml
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缓冲液
- Phosphate buffered saline
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C
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- HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
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物质类
- Viral Protein
抗原
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