CD19 抗体 (PE)
(8 references)Quick Overview for CD19 抗体 (PE) (ABIN638442)
抗原
See all CD19 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD19 PE
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特异性
- The mouse monoclonal antibody 4G7 recognizes an extracellular epitope of human CD19.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Human CCL (chronic lymphocytic leukemia) cells
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亚型
- IgG1 kappa
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anti-CD19 Molecule (CD19) (AA 151-250) antibody
CD19 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 20-291) antibodyCD19 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 8G11B7 unconjugated
anti-CD19 Molecule (CD19) (C-Term) antibodyCD19 适用: 人, 小鼠, 大鼠, 猴, 绵羊, Pig, Cow, 豚鼠, 兔, 犬, Avian, Cat, 小鸡, 驴, 山羊, Hamster, 马 WB 宿主: 山羊 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 485-556) antibodyCD19 适用: 人, 小鼠, 大鼠, 绵羊 FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (pTyr531) antibodyCD19 适用: 人, 小鼠 FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 96-281) antibodyCD19 适用: 人 FACS, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal CD19-3116 unconjugated
anti-CD19 Molecule (CD19) antibodyCD19 适用: 人 FACS, WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 143-172) antibodyCD19 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 160-258) antibodyCD19 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD19 Molecule (CD19) (AA 20-291) antibodyCD19 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4C6G1 unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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溶解方式
- No reconstitution is necessary.
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze.
Avoid prolonged exposure to light. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells." in: International journal of cancer. Journal international du cancer, Vol. 122, Issue 2, pp. 342-9, (2007) (PubMed).
: "Down-regulation of MLL-AF9, MLL and MYC expression is not obligatory for monocyte-macrophage maturation in AML-M5 cell lines carrying t(9;11)(p22;q23)." in: Oncology reports, Vol. 15, Issue 1, pp. 207-11, (2005) (PubMed).
: "Phenotypic and functional deficiencies of monocyte-derived dendritic cells in systemic lupus erythematosus (SLE) patients." in: International immunology, Vol. 16, Issue 11, pp. 1595-604, (2004) (PubMed).
: "Improved thymopoietic potential in aviremic HIV infected individuals treated with HAART by intermittent IL-2 administration." in: AIDS, Vol. 17, Issue 11, pp. 1621-30, (2003) (PubMed).
: "Cytofluorographic identification of activated T-cell subpopulations in the semen of men with spinal cord injuries." in: Journal of andrology, Vol. 23, Issue 4, pp. 551-6, (2002) (PubMed).
: "Selective attraction of naive and memory B cells by dendritic cells." in: Journal of leukocyte biology, Vol. 70, Issue 4, pp. 633-41, (2001) (PubMed).
: "Triggering Fc alpha-receptor I (CD89) recruits neutrophils as effector cells for CD20-directed antibody therapy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 10, pp. 5954-61, (2000) (PubMed).
: "Phenotypic and functional evidence for the expression of CD4 by hematopoietic stem cells isolated from human fetal liver." in: Blood, Vol. 89, Issue 4, pp. 1364-75, (1997) (PubMed).
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: "EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells." in: International journal of cancer. Journal international du cancer, Vol. 122, Issue 2, pp. 342-9, (2007) (PubMed).
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- CD19 (CD19 Molecule (CD19))
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别名
- CD19
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背景
- CD19 Molecule,CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.,B4, Leu-12, CVID3
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基因ID
- 930
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UniProt
- P15391
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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