IHC-P: 5 µg/mL Optimal conditions should be determined by the investigator.
限制
仅限研究用
浓度
Lot specific
缓冲液
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
储存液
Sodium azide
注意事项
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事项
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
抗原
USP33
(Ubiquitin Specific Peptidase 33 (USP33))
别名
USP33
背景
USP 33 is a deubiquitinating enzyme involved in various processes such as cellular migration and beta-2 adrenergicreceptor/ADRB2 recycling. It is involved in cell migration via its interaction with intracellular domain of ROBO1, leadingto regulation of Slit signaling. It also plays a role in commissural axon guidance cross the ventral midline of the neural tube in a Slit-dependent manner, possibly by mediating the deubiquitination of ROBO1. Acts as a regulator of G-proteincoupled receptor (GPCR) signaling by mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2) and beta-2adrenergic receptor (ADRB2).