PDE1C 抗体
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北京 101111
Quick Overview for PDE1C 抗体 (ABIN636953)
抗原
See all PDE1C 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity chromatography purified
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免疫原
- PDE1 C antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
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应用备注
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IHC-P: 5 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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浓度
- Lot specific
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缓冲液
- Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
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- PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
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别名
- PDE1C
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背景
- Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDE1, 2, 3, 10 and 11 degrade bothcyclic nucleotides. These enzymes are involved in many signal transduction pathways.
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
抗原
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