AGE 抗体
Quick Overview for AGE 抗体 (ABIN636761)
抗原
See all AGE 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- AGE antibody was raised in goat using glycoaldehyde-modified protein as the immunogen.
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应用备注
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ELISA: >1:4,000, WB: >1:2,000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Supplied as liquid whole serum without preservative
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- AGE (Advanced Glycation End Products (AGE))
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别名
- AGE
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物质类
- Chemical
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背景
- Glycation is a post-translational modification of proteins involving a covalent linkage between a reducing sugar, such as glucose, and a receptive amino group via the non-enzymatic Maillard reaction. During the early stages of the Maillard reaction, the aldehyde groups of the reducing sugars react with the amino groups of N-terminal amino acids to form Schiff bases, which are then converted to Amadori compounds. In the advanced stages, these Amadori compounds undergo oxidation, dehydration and condensation to form advanced glycation end-products (AGE) that are characterized by fluorescence, browning, and intra- or inter-molecular cross-linking properties. The main AGE products are pentosine and carboxymethyllysine (CML).
抗原
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