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Oncostatin M 抗体

OSM 适用: 人 WB, ELISA, Inhibition 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN636696
发货至: 中国
  • 抗原 See all Oncostatin M (OSM) 抗体
    Oncostatin M (OSM)
    适用
    • 57
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    宿主
    • 60
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    克隆类型
    • 63
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    多克隆
    标记
    • 37
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    This Oncostatin M antibody is un-conjugated
    应用范围
    • 56
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    Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
    纯化方法
    Purified
    免疫原
    Oncostatin M antibody was raised in rabbit using highly pure recombinant human oncostatin M as the immunogen.
    Top Product
    Discover our top product OSM Primary Antibody
  • 应用备注
    ELISA: 0.5-2 µg/mL, Inhibition: 0.1-0.175 µg/mL, WB: 0.1-0.2 µg/mL
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized from PBS, pH 7.2.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • 抗原
    Oncostatin M (OSM)
    别名
    Oncostatin M (OSM 产品)
    别名
    OSM antibody, OncoM antibody, oncostatin M antibody, OSM antibody, Osm antibody
    背景
    Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activate T cells, monocytes and Kaposi’s sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi’s sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL6, and CNTF. Human OSM is active on Mouse cells.
    分子量
    23.9 kDa (predicted detection band MW)
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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