MIA 抗体
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北京 101111
Quick Overview for MIA 抗体 (ABIN636661)
抗原
See all MIA 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- MIA antibody was raised in rabbit using highly pure recombinant human MIA as the immunogen.
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应用备注
- Optimal conditions should be determined byt he investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, pH 7.2.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- MIA (Melanoma Inhibitory Activity (MIA))
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别名
- MIA
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背景
- MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family, MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis.
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分子量
- 12.2 kDa (predicted detection band MW)
抗原
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