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RELM alpha 抗体

There is 1 publication for this product available. The 兔 多克隆 anti-RELM alpha antibody is suitable to detect RELM alpha in samples from 小鼠. It has been validated for WB, ELISA 和 Inhibition.
产品编号 ABIN636644
发货至: 中国
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Quick Overview for RELM alpha 抗体 (ABIN636644)

抗原

See all RELM alpha 抗体
RELM alpha

适用

  • 29
  • 17
  • 4
小鼠

宿主

  • 32
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  • 1

克隆类型

  • 32
  • 3
多克隆

标记

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  • 1
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  • 1
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  • 1
  • 1
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This RELM alpha antibody is un-conjugated

应用范围

  • 35
  • 16
  • 13
  • 7
  • 2
Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
  • 纯化方法

    Purified

    免疫原

    RELM alpha antibody was raised in rabbit using highly pure recombinant murine RELMa as the immunogen.
  • 应用备注

    Optimal conditions should be determined byt he investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS, pH 7.2.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • Wang, Ismahil, Zhu, Rokosh, Hamid, Zhou, Pogwizd, Prabhu: "CD206+IL-4Rα+ Macrophages Are Drivers of Adverse Cardiac Remodeling in Ischemic Cardiomyopathy." in: Circulation, Vol. 152, Issue 4, pp. 257-273, (2025) (PubMed).

  • 抗原

    RELM alpha

    背景

    RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha re still unknown.

    分子量

    10.0 kDa (predicted detection band MW)
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