Adipolean (Variant) 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in ELISA, WB 和 Inhibition. Suitable for 人.
Quick Overview for Adipolean (Variant) 抗体 (ABIN636638)
抗原
Adipolean
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB), Blocking Antibody (Inhibition)
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抗原表位
- Variant
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纯化方法
- Purified
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免疫原
- Adipolean Variant antibody was raised in rabbit using highly pure recombinant human adipolean variant as the immunogen.
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应用备注
- Optimal conditions should be determined byt he investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, pH 7.2.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Adipolean
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背景
- The adipolean variant is an important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. It stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. The adipolean variant antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It also inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway.
抗原
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