CLCF1 抗体
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北京 101111
Quick Overview for CLCF1 抗体 (ABIN636624)
抗原
See all CLCF1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- NNT1 antibody was raised in rabbit using highly pure recombinant human NNT-1/BCSF-3 as the immunogen.
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应用备注
- Optimal conditions should be determined byt he investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, pH 7.2.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))
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别名
- NNT1
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背景
- NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM.
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分子量
- 22.4 kDa (predicted detection band MW)
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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