Cardiotrophin 1 抗体
Quick Overview for Cardiotrophin 1 抗体 (ABIN636549)
抗原
See all Cardiotrophin 1 (CTF1) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- Cardiotrophin 1 antibody was raised in rabbit using highly purerecombinant hCT-1 (human Cardiotrophin-1) as the immunogen.
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应用备注
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ELISA: 0.5-2 µg/mL, Inhibition: 0.25-0.4 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, pH 7.2.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Cardiotrophin 1 (CTF1)
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别名
- Cardiotrophin 1
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背景
- CT-1 is a member of the IL6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL11, IL6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201 amino acid polypeptide lacking a hydrophobic N-terminal secretion signal sequence.
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分子量
- 21.5 kDa (predicted detection band MW)
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途径
- JAK/STAT Signaling
抗原
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