EDAR 抗体 (Middle Region)
Quick Overview for EDAR 抗体 (Middle Region) (ABIN636121)
抗原
See all EDAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- Ectodysplasin A Receptor antibody was raised against the middle region of EDAR
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纯化方法
- Affinity purified
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免疫原
- Ectodysplasin A Receptor antibody was raised using the middle region of EDAR corresponding to a region with amino acids PAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGV
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Ectodysplasin A Receptor Blocking Peptide, (ABIN5613300), is also available for use as a blocking control in assays to test for specificity of this Ectodysplasin A Receptor antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of EDAR antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- EDAR (Ectodysplasin A Receptor (EDAR))
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别名
- Ectodysplasin A Receptor
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背景
- EDAR is a member of the tumor necrosis factor receptor family. It is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in the gene encoding EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
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分子量
- 48 kDa (MW of target protein)
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途径
- Tube Formation, Ubiquitin Proteasome Pathway
抗原
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