Klotho beta 抗体 (Middle Region)
Quick Overview for Klotho beta 抗体 (Middle Region) (ABIN635626)
抗原
See all Klotho beta (KLB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- Klotho Beta antibody was raised against the middle region of KLB
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纯化方法
- Affinity purified
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免疫原
- Klotho Beta antibody was raised using the middle region of KLB corresponding to a region with amino acids DAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGFSLKESTPDVQG
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anti-Klotho beta (KLB) (AA 380-506) antibody
KLB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Klotho beta (KLB) (AA 846-965) antibodyKLB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Klotho beta (KLB) (AA 517-636) antibodyKLB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Klotho beta (KLB) (AA 1-130) antibodyKLB 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Klotho beta (KLB) (AA 517-636) antibodyKLB 适用: 人 WB 宿主: 小鼠 Monoclonal 8# unconjugated
anti-Klotho beta (KLB) (AA 1-29) antibodyKLB 适用: 人 WB 宿主: 兔 Polyclonal RB55007 unconjugated
anti-Klotho beta (KLB) (AA 517-636) antibody (Biotin)KLB 适用: 人 WB 宿主: 兔 Polyclonal Biotin
anti-Klotho beta (KLB) (Internal Region) antibodyKLB 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Klotho Beta Blocking Peptide, (ABIN937254), is also available for use as a blocking control in assays to test for specificity of this Klotho Beta antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KLB antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Klotho beta (KLB)
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别名
- Klotho beta
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背景
- KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.
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分子量
- 120 kDa (MW of target protein)
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
抗原
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