MUL1 抗体 (Middle Region)
Quick Overview for MUL1 抗体 (Middle Region) (ABIN635254)
抗原
See all MUL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- C1 ORF166 antibody was raised against the middle region of C1 rf166
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纯化方法
- Affinity purified
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免疫原
- C1 ORF166 antibody was raised using the middle region of C1 rf166 corresponding to a region with amino acids KPLDSVDLGLETVYEKFHPSIQSFTDVIGHYISGERPKGIQETEEMLKVG
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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C1ORF166 Blocking Peptide, (ABIN939975), is also available for use as a blocking control in assays to test for specificity of this C1ORF166 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of C0 RF166 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
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别名
- C1ORF166
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背景
- C1orf166 encodes an ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
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分子量
- 40 kDa (MW of target protein)
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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