SPTLC1 抗体 (Middle Region)
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北京 101111
Quick Overview for SPTLC1 抗体 (Middle Region) (ABIN635127)
抗原
See all SPTLC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- SPTLC1 antibody was raised against the middle region of SPTLC1
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纯化方法
- Affinity purified
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免疫原
- SPTLC1 antibody was raised using the middle region of SPTLC1 corresponding to a region with amino acids ICPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGINIDDIDLI
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应用备注
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WB: 0.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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SPTLC1 Blocking Peptide, (ABIN939291), is also available for use as a blocking control in assays to test for specificity of this SPTLC1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SPTLC1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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: "Transcriptional Differences in Lipid-Metabolizing Enzymes in Murine Sebocytes Derived from Sebaceous Glands of the Skin and Preputial Glands." in: International journal of molecular sciences, Vol. 22, Issue 21, (2021) (PubMed).
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- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
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别名
- SPTLC1
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背景
- Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1.
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分子量
- 53 kDa (MW of target protein)
抗原
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