STEAP3 抗体 (C-Term)
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- 抗原 See all STEAP3 抗体
- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STEAP3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- STEAP3 antibody was raised against the C terminal of STEAP3
- 纯化方法
- Affinity purified
- 免疫原
- STEAP3 antibody was raised using the C terminal of STEAP3 corresponding to a region with amino acids VALVLSTLHTLTYGWTRAFEESRYKFYLPPTFTLTLLVPCVVILAKALFL
- Top Product
- Discover our top product STEAP3 Primary Antibody
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- 应用备注
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WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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STEAP3 Blocking Peptide, catalog no. 33R-9427, is also available for use as a blocking control in assays to test for specificity of this STEAP3 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of STEAP3 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
- 别名
- STEAP3 (STEAP3 产品)
- 别名
- STEAP3 antibody, 1010001D01Rik antibody, Tsap6 antibody, pHyde antibody, AHMIO2 antibody, STMP3 antibody, TSAP6 antibody, dudlin-2 antibody, STEAP3 metalloreductase antibody, STEAP family member 3 antibody, STEAP3 antibody, steap3 antibody, Steap3 antibody
- 背景
- AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT.
- 分子量
- 56 kDa (MW of target protein)
- 途径
- Transition Metal Ion Homeostasis
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