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STEAP3 抗体 (C-Term)

This anti-STEAP3 antibody is a 兔 多克隆 antibody detecting STEAP3 in WB. Suitable for 人.
产品编号 ABIN634853
发货至: 中国

Quick Overview for STEAP3 抗体 (C-Term) (ABIN634853)

抗原

See all STEAP3 抗体
STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

适用

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宿主

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克隆类型

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多克隆

标记

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This STEAP3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    STEAP3 antibody was raised against the C terminal of STEAP3

    纯化方法

    Affinity purified

    免疫原

    STEAP3 antibody was raised using the C terminal of STEAP3 corresponding to a region with amino acids VALVLSTLHTLTYGWTRAFEESRYKFYLPPTFTLTLLVPCVVILAKALFL
  • 应用备注

    WB: 0.25 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    STEAP3 Blocking Peptide, (ABIN5616436), is also available for use as a blocking control in assays to test for specificity of this STEAP3 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of STEAP3 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

    别名

    STEAP3

    背景

    AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT.

    分子量

    56 kDa (MW of target protein)

    途径

    Transition Metal Ion Homeostasis
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