STEAP3 抗体 (C-Term)
Quick Overview for STEAP3 抗体 (C-Term) (ABIN634853)
抗原
See all STEAP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- STEAP3 antibody was raised against the C terminal of STEAP3
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纯化方法
- Affinity purified
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免疫原
- STEAP3 antibody was raised using the C terminal of STEAP3 corresponding to a region with amino acids VALVLSTLHTLTYGWTRAFEESRYKFYLPPTFTLTLLVPCVVILAKALFL
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应用备注
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WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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STEAP3 Blocking Peptide, (ABIN5616436), is also available for use as a blocking control in assays to test for specificity of this STEAP3 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of STEAP3 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
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别名
- STEAP3
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背景
- AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT.
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分子量
- 56 kDa (MW of target protein)
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途径
- Transition Metal Ion Homeostasis
抗原
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