Seladin 1 抗体 (N-Term)
Quick Overview for Seladin 1 抗体 (N-Term) (ABIN634838)
抗原
See all Seladin 1 (DHCR24) 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- N-Term
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                                            特异性
- DHCR24 antibody was raised against the N terminal of DHCR24
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                                            纯化方法
- Affinity purified
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                                            免疫原
- DHCR24 antibody was raised using the N terminal of DHCR24 corresponding to a region with amino acids FLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSK
 
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                                            应用备注
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                        WB: 1 µg/mL
 Optimal conditions should be determined by the investigator.
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                                            说明
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                        DHCR24 Blocking Peptide, (ABIN938356), is also available for use as a blocking control in assays to test for specificity of this DHCR24 antibody 
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                                            限制
- 仅限研究用
 
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                                            状态
- Lyophilized
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                                            溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DHCR24 antibody in PBS
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                                            浓度
- Lot specific
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                                            缓冲液
- PBS
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                                            注意事项
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                        Avoid repeated freeze/thaw cycles. 
 Dilute only prior to immediate use.
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                                            储存条件
- 4 °C/-20 °C
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                                            储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
 
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    - Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
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                                            别名
- DHCR24
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                                            背景
- DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
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                                            分子量
- 58 kDa (MW of target protein)
 抗原
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