Quick Overview for Glyco 抗体 (ABIN634766)
抗原
Glyco
适用
人
宿主
兔
克隆类型
多克隆
应用范围
Western Blotting (WB)
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纯化方法
- Affinity purified
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免疫原
- Glycoprotein Ib antibody was raised using a synthetic peptide corresponding to a region with amino acids RGSLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGRGQDLLSTVSIRYS
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应用备注
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WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Glycoprotein Ib Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this Glycoprotein Ib antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GP0 A antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Glyco
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物质类
- Viral Protein
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背景
- Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. GP1BA is the alpha subunit.
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分子量
- 68 kDa (MW of target protein)
抗原
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