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EPOR 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects EPOR in WB. It exhibits reactivity toward 人 和 犬.
产品编号 ABIN634567
发货至: 中国
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Quick Overview for EPOR 抗体 (N-Term) (ABIN634567)

抗原

EPOR (Erythropoietin Receptor (EPOR))

适用

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  • 52
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  • 3
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  • 1
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人, 犬

宿主

  • 104
  • 28
  • 3
  • 2
  • 2
  • 1

克隆类型

  • 109
  • 30
  • 1
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
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  • 1
This EPOR antibody is un-conjugated

应用范围

  • 98
  • 43
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  • 18
  • 14
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  • 5
  • 5
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  • 1
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 16
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    • 3
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    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    EPOr antibody was raised against the N terminal of EPOR

    纯化方法

    Affinity purified

    免疫原

    EPOr antibody was raised using the N terminal of EPOR corresponding to a region with amino acids DHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELL
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    EPOr Blocking Peptide, (ABIN937364), is also available for use as a blocking control in assays to test for specificity of this EPOr antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of EPOR antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    EPOR (Erythropoietin Receptor (EPOR))

    别名

    EPOr

    背景

    The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.

    分子量

    53 kDa (MW of target protein)

    途径

    JAK/STAT Signaling
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