HFE 抗体 (C-Term)
Quick Overview for HFE 抗体 (C-Term) (ABIN634557)
抗原
See all HFE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- HFE antibody was raised against the C terminal of HFE
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纯化方法
- Affinity purified
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免疫原
- HFE antibody was raised using the C terminal of HFE corresponding to a region with amino acids FEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS
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应用备注
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WB: 0.25 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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HFE Blocking Peptide, (ABIN938265), is also available for use as a blocking control in assays to test for specificity of this HFE antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HFE antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- HFE (Hemochromatosis (HFE))
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别名
- HFE
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背景
- HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
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分子量
- 28 kDa (MW of target protein)
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途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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