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HFE 抗体 (C-Term)

This anti-HFE antibody is a 兔 多克隆 antibody detecting HFE in WB 和 IHC. Suitable for 人.
产品编号 ABIN634557
发货至: 中国

Quick Overview for HFE 抗体 (C-Term) (ABIN634557)

抗原

See all HFE 抗体
HFE (Hemochromatosis (HFE))

适用

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宿主

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克隆类型

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多克隆

标记

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This HFE antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    特异性

    HFE antibody was raised against the C terminal of HFE

    纯化方法

    Affinity purified

    免疫原

    HFE antibody was raised using the C terminal of HFE corresponding to a region with amino acids FEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS
  • 应用备注

    WB: 0.25 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    HFE Blocking Peptide, (ABIN938265), is also available for use as a blocking control in assays to test for specificity of this HFE antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HFE antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    HFE (Hemochromatosis (HFE))

    别名

    HFE

    背景

    HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.

    分子量

    28 kDa (MW of target protein)

    途径

    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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