GADD45B 抗体 (Middle Region)
Quick Overview for GADD45B 抗体 (Middle Region) (ABIN634503)
抗原
See all GADD45B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- GADD45 B antibody was raised against the middle region of GADD45
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纯化方法
- Affinity purified
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免疫原
- GADD45 B antibody was raised using the middle region of GADD45 corresponding to a region with amino acids FCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHCLLVTNPHTDAW
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应用备注
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WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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GADD45B Blocking Peptide, (ABIN938237), is also available for use as a blocking control in assays to test for specificity of this GADD45B antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GADD40 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
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别名
- GADD45B
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背景
- GADD45B is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
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分子量
- 18 kDa (MW of target protein)
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途径
- Cell Division Cycle
抗原
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