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IL-15 抗体 (N-Term)

This anti-IL-15 antibody is a 兔 多克隆 antibody detecting IL-15 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN634483
发货至: 中国

Quick Overview for IL-15 抗体 (N-Term) (ABIN634483)

抗原

See all IL-15 (IL15) 抗体
IL-15 (IL15) (Interleukin 15 (IL15))

适用

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人, 小鼠, 大鼠

宿主

  • 97
  • 31
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克隆类型

  • 106
  • 36
多克隆

标记

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This IL-15 antibody is un-conjugated

应用范围

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  • 1
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  • 1
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Western Blotting (WB)
  • 抗原表位

    • 49
    • 5
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    N-Term

    特异性

    IL15 antibody was raised against the N terminal of IL15

    纯化方法

    Affinity purified

    免疫原

    IL15 antibody was raised using the N terminal of IL15 corresponding to a region with amino acids RISKPHLRSISIQCYLCLLLNSHFLTEAGIHVFILGCFSAGLPKTEANWV
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    IL15 Blocking Peptide, (ABIN5614168), is also available for use as a blocking control in assays to test for specificity of this IL15 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IL15 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    IL-15 (IL15) (Interleukin 15 (IL15))

    别名

    IL15

    背景

    IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.

    分子量

    13 kDa (MW of target protein)

    途径

    JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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