Doublecortin 抗体
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北京 101111
Quick Overview for Doublecortin 抗体 (ABIN634473)
抗原
See all Doublecortin (DCX) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purified
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免疫原
- DCX antibody was raised using a synthetic peptide corresponding to a region with amino acids TAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPIS
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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DCX Blocking Peptide, (ABIN5613146), is also available for use as a blocking control in assays to test for specificity of this DCX antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DCX antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Doublecortin (DCX)
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别名
- DCX
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背景
- In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The protein contains two doublecortin domains, which bind microtubules. In addition, DCX interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex.
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分子量
- 49 kDa (MW of target protein)
抗原
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