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NKIRAS1 抗体 (N-Term)

This anti-NKIRAS1 antibody is a 兔 多克隆 antibody detecting NKIRAS1 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN634451
发货至: 中国

Quick Overview for NKIRAS1 抗体 (N-Term) (ABIN634451)

抗原

See all NKIRAS1 抗体
NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This NKIRAS1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    NKIRAS1 antibody was raised against the N terminal of NKIRAS1

    纯化方法

    Affinity purified

    免疫原

    NKIRAS1 antibody was raised using the N terminal of NKIRAS1 corresponding to a region with amino acids CETMEDVYMASVETDRGVKEQLHLYDTRGLQEGVELPKHYFSFADGFVLV
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    NKIRAS1 Blocking Peptide, catalog no. 33R-1680, is also available for use as a blocking control in assays to test for specificity of this NKIRAS1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NKIRAS1 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

    别名

    NKIRAS1

    背景

    NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

    分子量

    22 kDa (MW of target protein)
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