Inhibin alpha 抗体 (N-Term)
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Quick Overview for Inhibin alpha 抗体 (N-Term) (ABIN634265)
抗原
See all Inhibin alpha (INHA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Inhibin Alpha antibody was raised against the N terminal of INHA
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纯化方法
- Affinity purified
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免疫原
- Inhibin Alpha antibody was raised using the N terminal of INHA corresponding to a region with amino acids GLAQEAEEGLFRYMFRPSQHTRSRQVTSAQLWFHTGLDRQGTAASNSSEP
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Inhibin Alpha Blocking Peptide, (ABIN938770), is also available for use as a blocking control in assays to test for specificity of this Inhibin Alpha antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of INHA antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
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别名
- Inhibin alpha
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背景
- INHA joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
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分子量
- 40 kDa (MW of target protein)
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途径
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
抗原
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