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Inhibin alpha 抗体 (N-Term)

The 兔 多克隆 anti-Inhibin alpha antibody is suitable to detect Inhibin alpha in samples from 人. It has been validated for WB.
产品编号 ABIN634265
发货至: 中国
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Quick Overview for Inhibin alpha 抗体 (N-Term) (ABIN634265)

抗原

See all Inhibin alpha (INHA) 抗体
Inhibin alpha (INHA) (Inhibin, alpha (INHA))

适用

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宿主

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克隆类型

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多克隆

标记

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This Inhibin alpha antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    Inhibin Alpha antibody was raised against the N terminal of INHA

    纯化方法

    Affinity purified

    免疫原

    Inhibin Alpha antibody was raised using the N terminal of INHA corresponding to a region with amino acids GLAQEAEEGLFRYMFRPSQHTRSRQVTSAQLWFHTGLDRQGTAASNSSEP
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    Inhibin Alpha Blocking Peptide, (ABIN938770), is also available for use as a blocking control in assays to test for specificity of this Inhibin Alpha antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of INHA antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    Inhibin alpha (INHA) (Inhibin, alpha (INHA))

    别名

    Inhibin alpha

    背景

    INHA joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.

    分子量

    40 kDa (MW of target protein)

    途径

    Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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