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Hexokinase 2 抗体 (N-Term)

This anti-Hexokinase 2 antibody is a 兔 多克隆 antibody detecting Hexokinase 2 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN634132
发货至: 中国

Quick Overview for Hexokinase 2 抗体 (N-Term) (ABIN634132)

抗原

See all Hexokinase 2 (HK2) 抗体
Hexokinase 2 (HK2)

适用

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人, 小鼠, 大鼠

宿主

  • 76
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克隆类型

  • 74
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多克隆

标记

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This Hexokinase 2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    Hexokinase 2 antibody was raised against the N terminal of HK2

    纯化方法

    Affinity purified

    免疫原

    Hexokinase 2 antibody was raised using the N terminal of HK2 corresponding to a region with amino acids GTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSG
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    Hexokinase 2 Blocking Peptide, (ABIN938992), is also available for use as a blocking control in assays to test for specificity of this Hexokinase 2 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HK2 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    Hexokinase 2 (HK2)

    别名

    Hexokinase 2

    背景

    Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK2 (hexokinase 2) is the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this protein is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway.

    分子量

    102 kDa (MW of target protein)

    途径

    PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect
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