P4HB 抗体 (C-Term)
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- 抗原 See all P4HB 抗体
- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This P4HB antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- P4 HB antibody was raised against the C terminal of P4 B
- 纯化方法
- Affinity purified
- 免疫原
- P4 HB antibody was raised using the C terminal of P4 B corresponding to a region with amino acids DRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDD
- Top Product
- Discover our top product P4HB Primary Antibody
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- 应用备注
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WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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P4HB Blocking Peptide, catalog no. 33R-2152, is also available for use as a blocking control in assays to test for specificity of this P4HB antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of P0 B antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
- 别名
- P4HB (P4HB 产品)
- 背景
- P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.
- 分子量
- 55 kDa (MW of target protein)
- 途径
- Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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