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P4HB 抗体 (N-Term)

P4HB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN633962
发货至: 中国
  • 抗原 See all P4HB 抗体
    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
    抗原表位
    • 21
    • 19
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    • 11
    • 5
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    • 2
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    N-Term
    适用
    • 106
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    • 10
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    人, 小鼠, 大鼠
    宿主
    • 118
    • 25
    • 2
    克隆类型
    • 109
    • 36
    多克隆
    标记
    • 61
    • 16
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    This P4HB antibody is un-conjugated
    应用范围
    • 111
    • 68
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    • 36
    • 18
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    • 5
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    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    P4 HB antibody was raised against the N terminal of P4 B
    纯化方法
    Affinity purified
    免疫原
    P4 HB antibody was raised using the N terminal of P4 B corresponding to a region with amino acids TIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLV
    Top Product
    Discover our top product P4HB Primary Antibody
  • 应用备注
    WB: 0.5 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    P4HB Blocking Peptide, catalog no. 33R-9118, is also available for use as a blocking control in assays to test for specificity of this P4HB antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of P0 B antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
    别名
    P4HB (P4HB 产品)
    别名
    DSI antibody, ERBA2L antibody, GIT antibody, P4Hbeta antibody, PDI antibody, PDIA1 antibody, PHDB antibody, PO4DB antibody, PO4HB antibody, PROHB antibody, PDA2 antibody, PDIP antibody, PDIR antibody, ERp59 antibody, Pdia1 antibody, Thbp antibody, p55 antibody, XPDIp antibody, pdi antibody, 1810041F13Rik antibody, AI661267 antibody, Pdip antibody, Pdipl antibody, p58 antibody, prolyl 4-hydroxylase subunit beta antibody, protein disulfide isomerase family A member 2 antibody, prolyl 4-hydroxylase, beta polypeptide antibody, protein disulfide isomerase family A member 2 L homeolog antibody, protein disulfide isomerase associated 2 antibody, prolyl 4-hydroxylase subunit beta L homeolog antibody, protein disulfide-isomerase antibody, P4HB antibody, PDIA2 antibody, P4hb antibody, pdia2.L antibody, Pdia2 antibody, p4hb.L antibody, LOC8281065 antibody
    背景
    P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.
    分子量
    55 kDa (MW of target protein)
    途径
    Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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