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P4HB 抗体 (N-Term)

This 兔 多克隆 anti-P4HB antibody specifically detects P4HB in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN633962
发货至: 中国
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Quick Overview for P4HB 抗体 (N-Term) (ABIN633962)

抗原

See all P4HB 抗体
P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This P4HB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    特异性

    P4 HB antibody was raised against the N terminal of P4 B

    纯化方法

    Affinity purified

    免疫原

    P4 HB antibody was raised using the N terminal of P4 B corresponding to a region with amino acids TIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLV
  • 应用备注

    WB: 0.5 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    P4HB Blocking Peptide, (ABIN5615176), is also available for use as a blocking control in assays to test for specificity of this P4HB antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of P0 B antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

    别名

    P4HB

    背景

    P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

    分子量

    55 kDa (MW of target protein)

    途径

    Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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