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APOE 抗体 (N-Term)

The 兔 多克隆 anti-APOE antibody (ABIN633837) specifically detects APOE in WB. The antibody is reactive with 人 samples.
产品编号 ABIN633837
发货至: 中国
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Quick Overview for APOE 抗体 (N-Term) (ABIN633837)

抗原

See all APOE 抗体
APOE (Apolipoprotein E (APOE))

适用

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宿主

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克隆类型

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多克隆

标记

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This APOE antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    ApoE antibody was raised against the N terminal of APOE

    纯化方法

    Affinity purified

    免疫原

    ApoE antibody was raised using the N terminal of APOE corresponding to a region with amino acids KVLWAALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRF
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    ApoE Blocking Peptide, (ABIN940102), is also available for use as a blocking control in assays to test for specificity of this ApoE antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of APOE antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    ApoE

    背景

    Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

    分子量

    34 kDa (MW of target protein)

    途径

    Regulation of Cell Size, Lipid Metabolism
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