CHRNA4 抗体 (N-Term)
Quick Overview for CHRNA4 抗体 (N-Term) (ABIN633758)
抗原
See all CHRNA4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- CHRNA4 antibody was raised against the N terminal of CHRNA4
-
纯化方法
- Affinity purified
-
免疫原
- CHRNA4 antibody was raised using the N terminal of CHRNA4 corresponding to a region with amino acids AEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTT
-
-
-
-
应用备注
-
WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
-
CHRNA4 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CHRNA4 antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CHRNA4 antibody in PBS
-
浓度
- Lot specific
-
缓冲液
- PBS
-
注意事项
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
-
别名
- CHRNA4
-
背景
- CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described.
-
分子量
- 67 kDa (MW of target protein)
-
途径
- Synaptic Membrane
抗原
-