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CHRNA4 抗体 (N-Term)

The 兔 多克隆 anti-CHRNA4 antibody is suitable to detect CHRNA4 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN633758
发货至: 中国
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Quick Overview for CHRNA4 抗体 (N-Term) (ABIN633758)

抗原

See all CHRNA4 抗体
CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

适用

  • 39
  • 19
  • 17
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 35
  • 5
  • 1

克隆类型

  • 26
  • 15
多克隆

标记

  • 25
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This CHRNA4 antibody is un-conjugated

应用范围

  • 32
  • 12
  • 7
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    CHRNA4 antibody was raised against the N terminal of CHRNA4

    纯化方法

    Affinity purified

    免疫原

    CHRNA4 antibody was raised using the N terminal of CHRNA4 corresponding to a region with amino acids AEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTT
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    CHRNA4 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CHRNA4 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CHRNA4 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

    别名

    CHRNA4

    背景

    CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described.

    分子量

    67 kDa (MW of target protein)

    途径

    Synaptic Membrane
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