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IFIH1 抗体 (Middle Region)

The 兔 多克隆 anti-IFIH1 antibody (ABIN633360) specifically detects IFIH1 in WB 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN633360
发货至: 中国
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Quick Overview for IFIH1 抗体 (Middle Region) (ABIN633360)

抗原

See all IFIH1 抗体
IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

适用

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  • 16
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  • 1

宿主

  • 49
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  • 2
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克隆类型

  • 39
  • 22
多克隆

标记

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  • 1
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This IFIH1 antibody is un-conjugated

应用范围

  • 46
  • 20
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  • 7
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  • 2
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    • 1
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    Middle Region

    特异性

    IFIH1 antibody was raised against the middle region of IFIH1

    纯化方法

    Affinity purified

    免疫原

    IFIH1 antibody was raised using the middle region of IFIH1 corresponding to a region with amino acids QINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDSDEGGDDEYCDGDEDED
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    IFIH1 Blocking Peptide, (ABIN5614142), is also available for use as a blocking control in assays to test for specificity of this IFIH1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IFIH1 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

    别名

    IFIH1

    背景

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. IFIH1 is a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation.

    分子量

    117 kDa (MW of target protein)

    途径

    Activation of Innate immune Response
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