IFIH1 抗体 (Middle Region)
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北京 101111
Quick Overview for IFIH1 抗体 (Middle Region) (ABIN633360)
抗原
See all IFIH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- IFIH1 antibody was raised against the middle region of IFIH1
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纯化方法
- Affinity purified
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免疫原
- IFIH1 antibody was raised using the middle region of IFIH1 corresponding to a region with amino acids QINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDSDEGGDDEYCDGDEDED
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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IFIH1 Blocking Peptide, (ABIN5614142), is also available for use as a blocking control in assays to test for specificity of this IFIH1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IFIH1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
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别名
- IFIH1
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背景
- DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. IFIH1 is a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation.
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分子量
- 117 kDa (MW of target protein)
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途径
- Activation of Innate immune Response
抗原
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