ALDH1A1 抗体 (Middle Region)
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北京 101111
Quick Overview for ALDH1A1 抗体 (Middle Region) (ABIN633157)
抗原
See all ALDH1A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- ALDH1 A1 antibody was raised against the middle region of ALDH1 1
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纯化方法
- Affinity purified
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免疫原
- ALDH1 A1 antibody was raised using the middle region of ALDH1 1 corresponding to a region with amino acids SVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGG
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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ALDH1A1 Blocking Peptide, (ABIN5612008), is also available for use as a blocking control in assays to test for specificity of this ALDH1A1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ALDH0 1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
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别名
- ALDH1A1
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背景
- This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.
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分子量
- 55 kDa (MW of target protein)
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途径
- Dopaminergic Neurogenesis
抗原
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