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GAD 抗体

The 兔 多克隆 anti-GAD antibody (ABIN633036) specifically detects GAD in WB. The antibody is reactive with 人 samples.
产品编号 ABIN633036
发货至: 中国
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Quick Overview for GAD 抗体 (ABIN633036)

抗原

See all GAD (GAD1) 抗体
GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

适用

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宿主

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克隆类型

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多克隆

标记

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This GAD antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 纯化方法

    Affinity purified

    免疫原

    GAD1 antibody was raised using a synthetic peptide corresponding to a region with amino acids MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGF
  • 应用备注

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    GAD1 Blocking Peptide, (ABIN5613699), is also available for use as a blocking control in assays to test for specificity of this GAD1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GAD1 antibody in PBS

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原

    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

    别名

    GAD1

    背景

    This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67 kDa form and a less-frequent 25 kDa form.

    分子量

    67 kDa (MW of target protein)
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