CA5B 抗体 (N-Term)
Quick Overview for CA5B 抗体 (N-Term) (ABIN633032)
抗原
See all CA5B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Carbonic Anhydrase Vb antibody (Mitochondrial) was raised against the N terminal of CA5 B
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纯化方法
- Affinity purified
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免疫原
- Carbonic Anhydrase Vb antibody (Mitochondrial) was raised using the N terminal of CA5 B corresponding to a region with amino acids WRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTDKSVIKGGPL
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Carbonic Anhydrase Vb Blocking Peptide (Mitochondrial), (ABIN5612606), is also available for use as a blocking control in assays to test for specificity of this Carbonic Anhydrase Vb antibody (Mitochondrial)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CA0 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- CA5B (Carbonic Anhydrase VB, Mitochondrial (CA5B))
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别名
- Carbonic Anhydrase Vb
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背景
- Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.
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分子量
- 33 kDa (MW of target protein)
抗原
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