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- 抗原 See all SMG8 抗体
- SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMG8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- C17 ORF71 antibody was raised against the middle region of C17 rf71
- 纯化方法
- Affinity purified
- 免疫原
- C17 ORF71 antibody was raised using the middle region of C17 rf71 corresponding to a region with amino acids HCVHKFHSLPKSGEKPEADRNPPVLYHNSRARSTGACNCGRKQAPRDDPF
- Top Product
- Discover our top product SMG8 Primary Antibody
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anti-Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) antibody
SMG8 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) (AA 575-624) antibodySMG8 适用: 人, 小鼠, Cow, 兔, 马, Pig, 大鼠, 犬, 豚鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) (Middle Region) antibodySMG8 适用: 人, 小鼠, Cow, 兔, 马, 大鼠, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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C17ORF71 Blocking Peptide, catalog no. 33R-3702, is also available for use as a blocking control in assays to test for specificity of this C17ORF71 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of C10 RF71 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
- 别名
- C17ORF71 (SMG8 产品)
- 别名
- C17orf71 antibody, 1200011M11Rik antibody, C19H17orf71 antibody, SMG8, nonsense mediated mRNA decay factor antibody, smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, Protein smg-8 antibody, SMG8 antibody, Smg8 antibody, smg-8 antibody
- 背景
- The C17ORF71 protein is a component of the SMG1C complex, a mRNA surveillance complex that recognises and degrades mRNAs containing premature translation termination codons (PTCs) via the nonsense-mediated mRNA decay (NMD). The complex probably acts by associating with ribosomes during tranlation termination on mRNPs. If an exon junction complex (EJC) is located 50-55 or more nucleotides downstream from the termination codon, SMG1 phosphorylates UPF1/RENT1, triggering nonsense-mediated mRNA decay (NMD).
- 分子量
- 110 kDa (MW of target protein)
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