SMG8 抗体 (Middle Region)
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北京 101111
Quick Overview for SMG8 抗体 (Middle Region) (ABIN632938)
抗原
See all SMG8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- C17 ORF71 antibody was raised against the middle region of C17 rf71
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纯化方法
- Affinity purified
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免疫原
- C17 ORF71 antibody was raised using the middle region of C17 rf71 corresponding to a region with amino acids HCVHKFHSLPKSGEKPEADRNPPVLYHNSRARSTGACNCGRKQAPRDDPF
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anti-Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) antibody
SMG8 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8) (AA 575-624) antibodySMG8 适用: 人, 小鼠, Cow, 马, Pig, 兔, 大鼠, Bat, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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C17ORF71 Blocking Peptide, (ABIN939088), is also available for use as a blocking control in assays to test for specificity of this C17ORF71 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of C10 RF71 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
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别名
- C17ORF71
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背景
- The C17ORF71 protein is a component of the SMG1C complex, a mRNA surveillance complex that recognises and degrades mRNAs containing premature translation termination codons (PTCs) via the nonsense-mediated mRNA decay (NMD). The complex probably acts by associating with ribosomes during tranlation termination on mRNPs. If an exon junction complex (EJC) is located 50-55 or more nucleotides downstream from the termination codon, SMG1 phosphorylates UPF1/RENT1, triggering nonsense-mediated mRNA decay (NMD).
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分子量
- 110 kDa (MW of target protein)
抗原
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