Caldesmon 抗体 (Middle Region)
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Quick Overview for Caldesmon 抗体 (Middle Region) (ABIN632441)
抗原
See all Caldesmon (CALD1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- Caldesmon 1 antibody was raised against the middle region of CALD1
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纯化方法
- Affinity purified
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免疫原
- Caldesmon 1 antibody was raised using the middle region of CALD1 corresponding to a region with amino acids FSSPTAAGTPNKETAGLKVGVSSRINEWLTKTPDGNKSPAPKPSDLRPGD
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Caldesmon 1 Blocking Peptide, (ABIN938461), is also available for use as a blocking control in assays to test for specificity of this Caldesmon 1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CALD1 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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别名
- Caldesmon 1
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背景
- CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction.
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分子量
- 63 kDa (MW of target protein)
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途径
- Myometrial Relaxation and Contraction
抗原
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