Carabin 抗体 (N-Term)
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Quick Overview for Carabin 抗体 (N-Term) (ABIN632187)
抗原
See all Carabin (TBC1D10C) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- TBC1 D11 antibody was raised against the N terminal of TBC1 11
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纯化方法
- Affinity purified
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免疫原
- TBC1 D11 antibody was raised using the N terminal of TBC1 11 corresponding to a region with amino acids MAQALGEDLVQPPELQDDSSSLGSDSELSGPGPYRQADRYGFIGGSSAEP
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应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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TBC1D10C Blocking Peptide, (ABIN5616511), is also available for use as a blocking control in assays to test for specificity of this TBC1D10C antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TBC0 10 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))
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别名
- TBC1D10C
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背景
- TBC1D10C inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. TBC1D10C acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.Carabin is an endogenous inhibitor of calcineurin that also inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein activity.
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分子量
- 50 kDa (MW of target protein)
抗原
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